API Process Development
Scintel Pharmachem Pvt Ltd’s chemical development team, comprising of seasoned scientists, practices a pragmatic culture in which scientists exceed expectations even on the most challenging projects. Working in state-of-the-art laboratories, equipped with the latest process and analytical instrumentation, Scintel’s scientists can efficiently conduct rapid process development, optimization of reaction conditions and scale-up of materials for preclinical trials or large – scale manufacturing.
Examples of Scintel’s services are
- Custom synthesis
- Process safety Assignment
- Scale –up Capabilities
- Thorough literature
- Route scouting and development of new synthetic routes for target molecules
- Optimization of reaction conditions to reduce cost and maximize throughput by classical methods or statistical design of experiments (DOE)
- Development of reliable methods for in- process testing and analysis of intermediates and APIs
- Development of robust crystallization or purification processes for intermediates and final products
- Ability to perform work under cryogenic conditions (-78 °C) or high pressures (> 100 psi)
- Preparation of API’s for non-clinical safety studies (NCSS) under GLP conditions
- Rapid screening of reactions conditions by utilizing parallel equipment
- Critical process parameter assessment
- Development of continuous flow processes